Is it possible to do it at the same time?
According to the order of the Russian Ministry of Health dated December 29, 2014, number 951, tuberculin diagnostics can be more extensive. Mantoux and Diaskintest are done on the same day.
This is not prohibited, but the main condition is to administer vaccines on different hands. What is it and what is their difference?
Mantoux is an injection that is injected into the skin. It contains killed mycobacteria of the disease. Diaskintest is also an injection that is done intradermally, but contains only antigen proteins.
With the first method, a false positive result is present in cases where the body has had contact with other infections or people with tuberculosis. Diaskintest gives positive results only when the child is already infected or has tuberculosis. There is a difference; for reliability, two manipulations are performed at once.
Simultaneous manipulations place a significant burden on the immune system. Before you decide to do this, you should weigh the pros and cons.
Is it possible to do Diaskintest and Mantu at the same time?
Mantoux and Diaskintest are allowed to be administered at once, but the drugs must be administered in different hands.
Composition Mantoux - tuberculin - an extract from killed and processed tuberculosis bacteria. Diaskintest does not contain all tuberculin, but only antigen proteins. The first test will be positive if the child simply had contact with a sick person. Diaskintest is positive only if the disease is present.
To make the diagnosis more reliable, both procedures can be done on the same day. This is permitted at the legislative level (Order of the Ministry of Health).
Reasons for joint holding
Why is the Mantoux test and Diaskintest done at the same time? Since these two diagnostic procedures differ in their effect, outcome indicators will provide the opportunity to obtain more accurate information.
Such an examination is advisable if the parents are sure that the child was in contact with a tuberculosis patient. The sample and test can detect pathology even at an early stage. An active form of tuberculosis can also be detected.
If the father and mother cannot decide what to choose, in this case (in the absence of contraindications and the presence of strong immunity), the doctor may advise doing both.
Evaluation of results
As mentioned above, manipulations are performed on different hands. Three days later, the specialist evaluates the results and draws appropriate conclusions, taking into account Mantoux and Diaskintest. It is important to adhere to all post-vaccination rules so that the information is truthful. If the child wets the injection site, you need to tell the doctor about it.
A specialist always evaluates the size of the papule. Depending on this, a verdict is made.
Mantoux is positive and Diaskitest is negative
If the Mantoux is positive and the Diaskintest is negative, it means that the child has immunity after BCG. It is also assumed that there is MBC in the body, but they do not differ in their activity. To verify and clarify the result, it is advisable to re-test after a certain time. If parents do not want to wait, they seek advice from a TB specialist, who in turn prescribes additional diagnostics. If a disease is detected, treatment must begin.
There is also a variant of positive Mantoux - contact of the corresponding hand with water. It is important not to wet or treat the injection site with any antiseptic. If any actions were performed, the doctor will not be able to reliably assess how the body reacts to the vaccine.
With a negative Diaskintest, tuberculosis is rarely detected in humans, since this is a fairly reliable and effective diagnostic method.
Mantoux is negative and Diaskitest is positive
If the Mantoux reaction is negative, and the Diaskintest gave a positive result, the information here can be assessed in the same way as in the situation described above.
Most often, this manifestation indicates the presence of Koch's bacillus in the body. To confirm this, other diagnostic procedures are done. If the body is not infected, then there should be nothing on the hand where Diaskintest was done, since the antigen protein does not react to anything other than mycobacteria.
Mantoux positive and Diaskitest positive
There is undoubtedly an infection with the tuberculosis bacillus. Positive reactions on both hands are a reason to start immediate treatment. You must first visit a phthisiatrician and undergo other diagnostic measures. The latter usually determine the degree of infection and the form of tuberculosis.
If the condition is extremely serious, hospitalization cannot be avoided. Only health workers are able to provide all the necessary assistance to the patient. After this, the patient is usually transferred to outpatient treatment, where he continues to take the prescribed medications. In the future, you should plan a sanatorium-resort treatment that will consolidate the result and prevent the disease from worsening.
Mantoux negative and Diaskintest negative
If there are no papules and redness on the hands, this indicates negative results of both Mantoux and Diaskintest. This reaction indicates that the person has not had contact with mycobacteria, and there is no need to worry about anything. No further examination is required.
Next time, it is not recommended to do simultaneous diagnostics, as this is a lot of stress for the body.
The injection site may change due to other factors that have nothing to do with tuberculosis infection, these are:
- Allergic reaction to the components of the drug. In this case, swelling, rashes, ulcers, extensive hyperemia appear, and even body temperature rises. In severe cases, breathing difficulties are observed. To prevent the occurrence of anaphylactic shock and other equally dangerous manifestations, you should immediately go to the hospital. If the doctor sees something similar on the arm, this means that the child is contraindicated for further examination for tuberculosis in this way.
- Failure to comply with the rules in the post-vaccination period. Papule and redness sometimes occur if the hand is wet or treated with alcohol solutions, ointments or gels. Contact with any product is strictly prohibited. This can lead not only to a false positive result, but to various consequences.
- Incorrect administration of the drug. If the manipulation was carried out by an unqualified specialist, then a false result may also appear. To avoid such an excess, you must first make sure that the nurse has enough experience in performing such injections (if, of course, such a possibility exists).
- Carrying out tests and samples during a respiratory illness or an exacerbated chronic disease. If the child was not examined beforehand, or the doctor did not pay attention to the fact that he was sick, the immune system may not cope with the drug and react to it in all possible ways, not in favor of the patient. Naturally, after this, the current disease will take much longer to heal and the test itself will be false. As a result, you will have to re-diagnose.
In any case, only a doctor can decipher the result of one or another test.
Mantoux or Diaskintest? Two effective methods of immunodiagnosis
19.Mar.2021
Not long ago, scientists developed a new method for diagnosing tuberculosis - Diaskintest. What is Diaskintest? Diaskintest is a drug that makes it possible to confirm the presence or absence of tuberculosis microbacteria in the human body.
The test allows you to clearly differentiate the post-vaccination reaction, that is, the presence of immunity, from the infectious process, ensuring the absence of false-positive reactions, thanks to almost 100% specificity. Therefore, a skin test with Diaskintest, unlike the Mantoux test, is a marker of the activity of tuberculosis infection, and a positive reaction indicates the presence of either tuberculosis or a latent tuberculosis infection with a high risk of developing the disease, which is an indication for preventive treatment. The introduction of Diaskintest as a screening method for the early diagnosis of tuberculosis in children 8 years of age and older, due to the high specificity of this method, can significantly improve the quality of diagnosis.
How is the procedure performed? The Diaskintest test, reviews of which are currently mostly positive, is no different in method from the Mantoux reaction. As a result of the administration of the drug, it is possible to detect pathogens that are in the active reproduction phase. In this case, the test will be positive (a papule or redness of any size will be noted). If mycobacteria are in the latent phase in the body, the result will be negative.
I would like to tell parents not to refuse to visit a specialist if they have a positive reaction to the test. A TB doctor will examine the child and may prescribe preventive treatment. Preventive treatment with anti-tuberculosis drugs is prescribed not for the purpose of “poisoning the child,” but in order to prevent the transition of a latent infection into a real disease.
Also important for the prevention of tuberculosis is a balanced, nutritious diet with sufficient protein and vitamins in food, normalization of the study, work and rest regime, and the abandonment of bad habits by both adolescents and parents.
In conclusion, I would like to say that appointments with a TB specialist, examination and treatment are provided free of charge, regardless of whether you have an insurance policy or citizenship. For any questions that concern you, you can contact the pediatric phthisiatrician at the children's clinic.
Artanova M.V. phthisiatrician, Nyagan City Children's Clinic
Conclusion
Is it possible to do Manta and Diaskintest at the same time? In some cases, manipulations are carried out simultaneously. Such a decision should be deliberate, as this is a strong burden on the baby’s immunity. The two procedures differ in their action; together they can more accurately determine whether a person is infected or not.
If parents cannot choose which of the two examination methods is better or they are sure that their child was in close contact with an infected person, then Mantoux and Diaskintest are allowed to be carried out at the same time. If there is no need to rush, then Manta is done first, and then, after 14-21 days, Diaskintest. In this case, there is time to restore immunity after the first vaccination.
The results are assessed by a doctor after three days. It is important that the patient follows all the rules so that a false positive or false negative reaction does not occur. In different situations, other further actions are taken. If necessary (if both tests or only one are positive), additional diagnostics are recommended to rule out the presence of tubercle bacilli in the body. In case of unexpected wetness of the injection site, a repeat test is done after a certain period of time.
