Instructions for use of the drug Allokin-Alfa - composition, how to dilute, side effects and price

Allokin Alpha injections

This antiviral drug is used to treat such common diseases as papillomavirus and herpes. The causative agents of these pathologies live in the human body constantly, but make themselves felt only when the immune system is weakened. Symptoms of the disease can be reduced with the help of local remedies such as ointments, but the virus still remains active in the body. Injections of Allokin Alpha solution can suppress the action of pathogenic bacteria.

Compound

The main active component of the drug is a cytokine-like peptide called “alloferon”. This substance is produced through chemical synthesis and is a patented product in a number of countries, including the USA, Japan, and some European countries. Due to its uniqueness, Allokin Alpha has no analogues in structure, but only substitutes with a similar effect on the body and viruses.

Release form

The injection is produced in the form of a powder from which a solution is prepared. Allokin Alpha is packaged in ampoules of 1 mg. One package contains 1, 3, 5 or 10 injection doses, as well as a file for opening glass vessels. The shelf life of the drug is 2 years if stored at 2 to 8 degrees. In Russia, the medicine is produced by the following pharmaceutical companies:

• "Brand Pharm";
• “RKNPK Ministry of Health and Social Development - EPMBP”;
• State Research Institute of Especially Pure Biological Preparations FMBA Federal State Unitary Enterprise.

Pharmacodynamics and pharmacokinetics

Alloferon, which serves as the main active component of the drug, activates natural killer cells in the body and stimulates the production of endogenous interferons. In addition, the active substance quickly identifies and destroys cells infected with cytotoxic lymphocytic structures. During therapy with Allokin Alpha, the immune system is strengthened (the medication acts as an immunomodulator). Moreover, the drug has no toxic effects.

The main pharmacological effects of Allokin Alpha are:

• absolute relief from the symptoms of viral hepatitis, HPV, herpes infection;
• reducing the duration of exacerbation of pathology;
• reducing the likelihood of complications;
• guarantee of no relapse of the disease.

Under the influence of allofen, the action of T-lymphocytes, which constitute the immunity of cellular structures, is triggered. Such substances, during interaction with drugs, actively destroy the virus that has entered the human body. After a course of treatment with Allokin Alpha, stimulation of nerve impulses occurs, as a result of which neurocellular excitability is regulated. In addition, under the influence of the drug on smooth muscle tissue, the effect of histamine, serotonin, acetylcholine and oxytocin is enhanced.

Indications for use

Allokin Alpha is prescribed for severe immunodeficiency, which is often observed with viral infections. To prevent the progression of the pathological process, the drug is used as an immunomodulator. This antiviral medication is usually prescribed for the prevention of cervical cancer and treatment of:

• viral hepatitis types B or C;
• herpes;
• cervical erosion (the drug is prescribed by a gynecologist);
• condylomas, papillomas, warts;
• influenza, ARVI;
• HPV;
• labial herpes;
• genital herpes;
• mixed infections of urogenital localization.

Contraindications

The domestically produced product is widely used to suppress the human papillomavirus. Injections are effective in strengthening the immune system; in addition, they help increase the activity of T-lymphocytes, due to which viral cells divide more slowly and completely disintegrate. Allokin Alpha is contraindicated:

• to kid;
• pregnant or lactating woman;
• with pronounced autoimmune diseases;
• in the presence of intolerance or hypersensitivity to alloferon or other components of the drug.

Allokin Alpha - instructions for use

The drug stimulates the body's production of interferon, which strengthens the immune system and actively fights infections. Alloferon Alpha is a low-toxic medicine, therefore it does not cause allergic reactions, does not have a mutagenic, teratogenic or embryotoxic effect or a carcinogenic effect. However, like any other drug, it should be used as prescribed by a doctor and according to the instructions.

How to dilute the solution

The powder from one ampoule is mixed in an isotonic sodium chloride solution (1 ml). To prevent side effects, it is not recommended to dilute the product in other drugs. In addition, you cannot combine several medications in one medical syringe. The prepared solution should be used immediately after preparation, without leaving it until the next injection, since the medication quickly loses its therapeutic effect.

How to give an injection

Before the procedure, it is important to ensure thorough hygiene of the injection site; for this, the puncture area is treated with alcohol. How to inject Allokin Alpha yourself at home:

• the drug should be administered subcutaneously, for which the skin is gathered into a fold and a needle is inserted at an angle of 45 degrees;
• insertion of the needle should not be deep: you need to immerse it no more than 2/3 of the length;
• the medication is injected slowly and, as a rule, into the shoulder, thigh, abdomen or under the shoulder blade;
• The frequency of injections and concentration of Allokin Alpha is prescribed by the doctor, based on the type of disease, severity of symptoms, etc.

Dosage

The standard course of therapy with Allokin Alpha consists of three injections, which are given at intervals of a day. However, with severe pathology or advanced disease, the duration of the course increases, and the doctor adjusts the treatment regimen. To prepare the solution, it is important to use only the products specified in the instructions. Standard dosage for the treatment of viral diseases:

• for diseases caused by oncogenic types of papillomavirus, 1 ml of the drug is administered every second day, and treatment lasts 12 days;
• for the treatment of viral hepatitis C or B, 1 injection three times a week is indicated (9 procedures in total);
• after a relapse of herpes, the patient is given 1 ampoule of the drug every other day, and the course of treatment includes 3 injections.

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special instructions

During treatment with Allokin Alpha, you should avoid activities that require increased concentration and quick reaction, as there is a possibility of dizziness, drowsiness, and chills. In addition, it is important to be careful when driving a car, and, if possible, to completely abandon this activity during therapy. If the use of the drug is aimed at suppressing viral hepatitis, complex treatment begins 6-7 days later than the appearance of severe symptoms of jaundice such as:

• fever;
• darkening of urine;
• yellowing of the skin, eye sclera;
• pain in the right hypochondrium.

During pregnancy and lactation

Despite the fact that the main active ingredient Allokin Alpha does not produce any teratogenic or mutagenic effects, the use of the drug during pregnancy and breastfeeding is prohibited. If there is a need to use this medication for the treatment of viral pathologies, the child should be transferred to infant formula and weaned off the breast for the duration of therapy. Allokin Alpha and pregnancy are categorically incompatible.

Interaction with other drugs

Allokin Alpha for HPV and other viral diseases is often prescribed in combination with other drugs. For example, chronic herpes is treated by combining an injection medication with Acyclovir (or its analogues), since both drugs are antiviral and complement each other. To suppress hepatitis B, Allokin Alpha is used as part of basic therapy.

Interaction with alcohol

During treatment with the medication, it is necessary to avoid drinking alcohol, since Allokin Alpha increases the percentage of interferon in the blood, which is highly sensitive to any changes at the chemical level. The final reaction of the body can have unpredictable consequences. Despite the fact that no research has been conducted in this area, scientists have no doubt about the negative effects of mixing alcohol with the drug: this will, at a minimum, reduce the effectiveness of treatment, and in extreme cases, cause harm to health.

Side effects

Injections against HPV, hepatitis, herpes and other viruses are usually well tolerated by patients. However, in rare cases, the drug can provoke negative effects, which are often caused by an overdose of the drug, failure to comply with hygiene standards, or combination with other medications. Possible side effects:

• dizziness;
• muscle weakness;
• headache;
• decreased excitability of the nervous system;
• allergic reactions;
• the appearance of new foci of herpetic eruptions.

Allocoin-alpha during pregnancy

During pregnancy, you should stop taking this medication.
The substances included in the drug may have a negative effect on the fetus.

The use of the drug is also not allowed during breastfeeding. If the recommended requirements are not met, the child begins to develop serious diseases that become chronic. If it is not possible to replace the drug with a safe analogue, then the medication may be allowed, but only a doctor can decide this.

During menstruation, the use of the drug Allokin-alpha is allowed. If destruction is indicated (on the 6-7th day of treatment), then therapy begins on the first day of the cycle. If no destruction process is observed, then treatment can begin on any day.

Analogs

Some drugs produced in Russia and abroad have a similar effect to Allokin Alpha. Such funds include:

• Amizon;
• Arpeflu;
• Isoprinosine;
• Panavir;
• Oksolin;
• Amiksin;
• Kagocel;
• Groprinosin;
• Gardasil;
• Cervarix.

The main analogue of Allokin Alpha is Panavir, which has similar antiviral and immunomodulatory effects. The product has approximately the same cost and effectiveness, so it is difficult to determine which drug is better. Each doctor chooses a medication for a patient based on individual factors: the patient’s condition, type of pathology, degree of severity, etc.

Price Allokin Alpha

The cost of an antiviral drug is influenced by several factors - the number of ampoules in a box, production, pricing policy of the pharmacy and its location. You can buy Allokin Alpha only with a doctor’s prescription, certified by a stamp and signature. The table below shows the average cost of the drug in different pharmacies in Moscow.

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