Dosage of "Analgin" with "Diphenhydramine" for a child - instructions for use and reviews

Features of the drugs

"Analgin" is an anti-inflammatory drug belonging to the group of non-steroidal drugs. Injectable "Analgin" is packaged by the manufacturer in glass ampoules with a volume of 1 or 2 ml. The active component in the drug is sodium metamizole, the concentration of which in the injection solution "Analgin" is 25% or 50%. Each cardboard package may contain 5 or 10 ampoules of the drug. The solution contains, in addition to the active component, only sterile water.

What is the dosage of Analgin with Diphenhydramine for a baby? We'll talk about this below.

Dosage

If the dosage of any medication is violated, serious consequences can occur, including death. In this case, the violations will be expressed in severe convulsive syndrome, which is also sometimes fatal. It is best to entrust the calculation of the dose to qualified doctors who have been doing this for a long time and are unlikely to make a mistake, but if you have to provide first aid, then follow the instructions on how to inject Analgin with Diphenhydramine.

Pediatric dosage

Before calculating the dosage of Analgin and Diphenhydramine for children, it is important to consider all alternative options, because this combination can still pose a danger. For example, candles called Analdim are quite common, which already include these agents and are safe for children. As for the injection solution of Analgin with Diphenhydramine, adhere to the following rules:

• take 10 mg of Analgin per 1 kg of child’s body weight;
• take 0.41 mg of Diphenhydramine for each year of the child’s life.

Popular Ginipral - for normal labor

Draw these drugs into one syringe, and Analgin should be drawn first. Do not mix these medications under any circumstances by shaking them! It should be administered intramuscularly and at an extremely low speed.

Sometimes it is reasonable to add Papaverine to this combination, but this must also be agreed upon with the attending physician. Here is a list of side effects that can sometimes affect a child:

• nausea or even vomiting that does not bring any relief;
• tachycardia, that is, rapid heartbeat;
• increased sweating;
• disorders associated with intestinal function, namely, diarrhea often occurs or, conversely, constipation;
• deterioration of indicators related to blood tests (hemoglobin levels may drop seriously, and sometimes anemia is diagnosed).

Let us mention once again that the use of such drugs is exclusively an emergency measure, that is, they should under no circumstances be used for the purpose of treatment or anything else, their task is to improve the well-being of a patient in serious condition.

Adult dosage

The dosage of Diphenhydramine with Analgin for adults should also be done wisely, because dangerous consequences can occur for them too. The rules for administering Analgin with Diphenhydramine for adults are slightly different, because in this case the volumes are not calculated based on body weight and life expectancy. An adult will need 0.3 ml and 0.2 ml of Analgin and Diphenhydramine, respectively. This injection should be administered once, and its effect will last for 6 hours. In any case, it is better to consult your doctor, especially if the effect does not occur within half an hour.

If there are any alternative options, it is better to give preference to them, since Analgin with Diphenhydramine is an extremely potent and aggressive combination. If the injection was nevertheless given, then it will be necessary to take a blood test afterwards in order to assess the consequences of the administration of these drugs.

Analgin with Diphenhydramine can be administered only according to indications and in case of serious pathological conditions; it is better to do this when there is no possibility of seeing a doctor. Follow dosage and administration recommendations.

How to administer Analgin

Analgin can be administered either intramuscularly or intravenously, but intravenous administration should be carried out exclusively in a hospital setting. Intravenous use of this drug at home is unacceptable. In addition to the injectable Analgin, the manufacturer also produces a tablet medicine, and the tablets come with different dosages of the active substance.

The active component in the Diphenhydramine injection solution is diphenhydramine. It is an antihistamine that can act on H1 receptors, which are sensitive to histamine. The drug is produced packaged in glass ampoules, each of which contains 1 ml of the drug. Each milliliter of Diphenhydramine contains 10 mg of diphenhydramine. Ampoules are additionally packaged in cardboard boxes of 10 pieces. In addition, in the form of tablets with a concentration of the active substance of 50 mg.

Diphenhydramine with alcohol

Diphenhydramine in combination with any alcohol actually gives a strong effect. Side symptoms of this combination may include hallucinations, confusion, hallucinogenic delirium and other consequences. Large doses of diphenhydramine in combination with alcohol can simply kill a person. That is why you should avoid any alcohol while taking diphenhydramine.

Diphenhydramine was withdrawn from free sale in pharmacies, as cases of using this medicine in combination with alcohol have become more frequent in recent years. In order to buy diphenhydramine, you will need to have a prescription from your doctor.

"Diphenhydramine"

The injection solution can be used for intravenous and intramuscular administration. As in the case of Analgin, Diphenhydramine can be administered intravenously only under the supervision of medical personnel, and therefore such injections are prescribed only in a hospital setting. At home, the injection drug can only be administered intramuscularly.

You also need to correctly calculate the dosage of Analgin with Diphenhydramine for the child.

Reasons for using drugs together

"Analgin" and "Diphenhydramine" when used together enhance each other's therapeutic effects. Since these drugs, administered simultaneously, act quickly enough at elevated temperatures, their combination is called a lytic mixture. "Analgin", present in the mixture, acts as an antipyretic and analgesic.

If we consider Diphenhydramine, then its main task is to relax smooth muscle structures and eliminate swelling. In addition, Diphenhydramine has a sedative effect and is able to prevent the development of allergic responses to the joint administration of drugs.

The lytic mixture begins to act 10 minutes after it is administered intramuscularly. The therapeutic effect lasts for 4 hours. The main indication for the use of a combination of these drugs is the risk of fever in children. The injection is usually given at very high temperatures (more than 39 degrees), and also if there is a high probability of developing a convulsive condition.

The doctor knows what dosage of Analgin with Diphenhydramine will be optimal for a child.

Indications for use

A lytic mixture for fever for children is used to quickly alleviate the serious condition of the patient. It is used when the fever is more than 38˚C, and all other antipyretics have not given the expected result.

A lytic mixture is given to children if fever provokes seizures. Parents should carefully examine the condition of their sick child. If he has a fever, and his legs and arms are cold and his skin is too pale, he must be given medicine immediately.

Use of a combination of drugs in the treatment of children

In accordance with the instructions, it is allowed from the age of 3 months. However, at such an early age, the medication should be used only if there are compelling indications, and also under the supervision of a specialist. In addition, it is dangerous to give injections to children under 3 years of age. If therapy is intended for a baby up to one year old, the medicine should be administered exclusively intramuscularly.

Injectable Diphenhydramine can be used in the treatment of children from 1 year of age. If there is a need to administer a lytic mixture to a child 3-12 months old, you should replace Diphenhydramine with Suprastin, since this drug can be used for intramuscular administration in children from 1 month.

Contraindications to the use of a combination of drugs

Administration of the lytic mixture is contraindicated if the patient has the following physiological or pathological conditions:

1. Diabetes.
2. The likelihood of developing bronchospasm.
3. Kidney failure.
4. Serious liver pathologies.
5. Disturbances of hematopoietic processes.
6. Intolerance to any component of the lytic mixture.

In addition, it is prohibited to administer a combination of drugs in the presence of acute abdominal pain of unknown origin (elimination of pain can lead to difficulties in determining its causes and deterioration of the child’s condition).

The use of a lytic solution should be carried out with caution and under the supervision of medical personnel if a child patient has hypotension, allergies, bronchial asthma, or trauma. If there is even the slightest risk to the child’s health, you should refuse to use Analgin and opt for an antipyretic drug that is safer for children, for example, Paracetamol.

When using a combination of Analgin and Diphenhydramine, the following negative symptoms may develop:

1. Deterioration in the production of leukocytes, which in some cases leads to the development of agranulocytosis.
2. Disorders of the digestive tract.
3. Fainting.
4. Decreased blood pressure.
5. Allergic reactions.
6. A strong decrease in body temperature for a long time.

The use of increased doses of the lytic mixture can lead to the development of shortness of breath, abdominal pain, drowsiness, hemorrhages, convulsions, and other dangerous manifestations. Often children with symptoms of drug intoxication have to be hospitalized in order to maintain vital functions.

Side effects and contraindications

Using medications without the permission of your pediatrician can lead to side complications. And nalgin sometimes leads to the development of acute gastritis, which is accompanied by stomach pain and diarrhea. Sometimes medications cause a child to develop a skin rash, vomiting, and convulsions.

If you are allergic to the active components of one of the drugs, you should stop using the entire composition.

The lytic mixture cannot be used in the following cases:

• for acute abdominal pain, if there is a possibility of appendicitis;
• if you are allergic to the components of the mixture;
• children under 6 months;
• 3 hours after taking medications containing Analgin.

In case of an overdose, the child may experience vomiting, a sharp drop in temperature, and difficulty breathing. In this case, the use of medications should be stopped. The child's stomach is washed and given a large amount of liquid to drink. Be sure to give a sorbent (activated carbon or smecta).

If convulsions occur, you should call an ambulance.

Dosage of "Analgin" with "Diphenhydramine" for a child

If the child is under 8 years old, then it is recommended to calculate the dose of Analgin required for him, taking into account his weight. To determine the daily dose of the lytic mixture, you should multiply the child’s weight by 5 or 10. This calculation allows you to determine the number of milligrams of metamizole sodium permissible for use in a particular child.

The daily dosage of “Analgin” injections with “Diphenhydramine” for children obtained by this calculation method is divided into 2 or three doses. It is worth considering that each dose should not exceed 100 mg if the child is less than 3 years old, and 200 mg if the child is 3-8 years old. For children over 8 years old, a single dosage of Analgin is 250-300 mg, from 14 years old – up to 500 mg.

The dosage of Diphenhydramine is determined taking into account the age of the small patient:

1. Children 1-3 years old should be administered 0.5 ml of Diphenhydramine; if necessary, the dose can be doubled.
2. Children 4-6 years old – 1-1.5 ml.
3. Children 7-14 years old - 1.5-3 ml.

Diphenhydramine and analgin injections contraindications

Severe pain or a rapid increase in temperature to critical levels requires urgent action.

In this case, antipyretic and analgesic tablets or suppositories are often ineffective. A lytic mixture is used to relieve severe pain and quickly reduce temperature.

It must include Analgin with Diphenhydramine. These drugs interact to increase each other's effectiveness.

In what cases can it be used and contraindications?

The use of Analgin injections with Diphenhydramine is justified if the patient has a very high body temperature. Also, drugs are prescribed for long-term pain syndrome of various etiologies.

Since Analgin and Diphenhydramine eliminate inflammation, injections based on these drugs are given for inflammatory diseases. The medicinal mixture is prescribed after surgery, for neuralgia, myalgia, joint pathologies, burns, hepatic or renal colic.

Sometimes Diphenhydramine, Analgin and Papaverine are combined for fever. Triad is used as an emergency medical aid during surgical interventions to eliminate pain through muscle relaxation of the ducts, urinary tract and intestines.

Sometimes Analgin with Diphenhydramine is combined with Lidocaine. This combination does not accelerate the therapeutic effect, but increases the analgesic and antiphlogistic effect.

Analgin with Diphenhydramine – contraindications:

• Neuralgia
• Acute allergy
• Pathologies of the circulatory system
• Liver and kidney diseases
• Pregnancy
• Asthma
• Lactation
• Chronic hyperglycemia
• Heart failure
• Glaucoma
• Bladder dysfunction
• Age up to one year.

It is noteworthy that Diphenhydramine has a pronounced sedative effect and causes drowsiness. Therefore, while using an antihistamine, it is not recommended to engage in activities that require special attention.

https://youtube.com/watch?v=G7tKHckzrgs

Also, when administering a mixture of Diphenhydramine and Analgin, it is prohibited to drink alcohol. Alcohol can lead to intoxication and coma.

Dosing by age

Analgin with Diphenhydramine is best used for children in the form of rectal suppositories. The combination of an analgesic and antihistamine is found in the drug Analdim.

A suppository containing Analgin with Diphenhydramine is used for children in a certain dosage. Age 1-4 years – 100 mg per day, 4-12 years – 250 mg per day, over 12 years – 250 mg twice a day.

The dose of Analgin and Diphenhydramine for children (medicinal solution) is selected depending on the body weight and age of the child. Thus, the amount of analgesic is 10 ml/kg, antihistamine is 0.41 ml for 1 year.

If you often use Diphenhydramine and Analgin for a child’s fever, the likelihood of negative reactions increases. These are severe nausea, hyperhidrosis, anemia, cardiac dysfunction, diarrhea or constipation.

In pediatrics, injection administration of Diphenhydramine and Analgin is considered an emergency and one-time event. And before using medications, you should consult with your pediatrician, because exceeding the dosage, depending on the child’s condition, can cause seizures or lead to death.

If it is necessary to carry out an antipyretic procedure for fever in adults, then the following dosage is used: Analgin - 0.3 ml, Diphenhydramine 0.2 ml. The drugs are administered once, maximum twice, once a day.

You may prefer tablets to injections, but adults are recommended to take an injection of Analgin with Diphenhydramine, the dosage of which is described above. The tablets have a negative effect on the mucous membranes of the gastrointestinal tract, liver and kidneys.

The administration of drugs Analgin with Diphenhydramine (dosage 0.3 and 0.2 mm) is carried out according to the following scheme:

• The ampoules are wiped with ethanol and opened
• First, an analgesic is drawn into the syringe, and then an antihistamine.
• The drugs are administered intramuscularly very slowly.

After treatment it is necessary to donate blood for analysis. After all, potent medications affect the composition of the blood, which can change greatly.

If necessary, Analgin can be replaced by other antipyretics (Aspirin). Sometimes auxiliary medications are added to the lytic mixture in dosages for adults:

• Analgin, Papaverine (2 ml each), Diphenhydramine (1 ml)
• Lidocaine, Diphenhydramine, Analgin - 1 ml each.

Method of introducing the lytic mixture

To manipulate the administration of “Analgin” with “Diphenhydramine” during fever in children, you should use a sterile syringe with a long needle. The ampoule and the skin at the injection site must be disinfected, for example, by smearing it with medical alcohol. Before opening the ampoules, you should hold them in your hand for a while so that the medicine warms up.

In accordance with the annotation, it is forbidden to mix with other medications, so experts recommend drawing “Analgin” into a syringe, injecting it into the muscle, leaving the needle at the puncture site, and drawing “Diphenhydramine” into the same syringe and injecting it using the same needle. But, as practice shows, the drugs are often administered simultaneously. In this case, open the ampoules and draw the drugs into one syringe one by one. As a rule, it is advised to dial “Analgin” first, then “Diphenhydramine”.

It is recommended to inject into the muscle of the shoulder or thigh to ensure that the medications reach the muscle structures. When the drug is injected into or under the skin, an inflammatory reaction or irritation may occur. It is for this reason that it is not recommended to administer a mixture of medications into the buttock area, since the muscles of the buttocks are located quite deep.

How long does it take for Analgin and Diphenhydramine to work? Within 10-15 minutes after the injection, the temperature drops.

Pills

The lytic remedy for fever does not have to be given as an injection. If the child is conscious and not vomiting, he is allowed to be given pills. They should first be crushed into powder. Take this product with water.

True, improvement in the condition will occur only after 30 minutes. The patient's fever will subside, he will sweat a lot and want to sleep. Be sure to change wet clothes and change your baby into dry pajamas.

Analgin, Paracetamol, Suprastin

A child over three years old can be given a mixture of tablets. The product must first be prepared, that is, the tablets must be crushed into powder.

Lytic mixture for children in tablets (from the whole part):

1. Analgin: ¼.
2. Paracetamol: ¼.
3. Suprastin: ¼.

The powder is poured into a spoon and mixed with a small amount of boiled water. The medicinal mixture is washed down with warm tea or compote.

Analgin, Paracetamol, No-spa

If you don’t have Papaverine in your home medicine cabinet, you can replace it with No-shpa. The dosage of drugs of the same type is not changed.

Lytic mixture for children - dosage of the drug in tablets (from the whole part):

1. Analgin: ¼.
2. Paracetamol: ¼.
3. No-shpa: ¼.

Analgin should be used carefully to relieve fever. This remedy may irritate the stomach lining and lead to severe abdominal pain and diarrhea.

Baralgin, Papaverine, Suprastin

The dosage of the drug is prescribed by the doctor based on the severity of the disease and the age of the baby. You can give children only minimal doses of the drug on your own. For example: an adult is given one whole tablet of each remedy for fever at one time.

Lytic mixture for children - composition (from the whole part):

1. Baralgin: ¼.
2. Papaverine: ¼.
3. Suprastin: ¼.

Before using crushed tablets, it is recommended to consult a doctor. Exceeding the dosage is not allowed. After 6 hours, if the fever does not subside, you can take the drug again in the same proportions.

Using a lytic mixture to eliminate white hyperthermia

Doctors use this term to describe a condition when a child experiences not only a significant increase in temperature, but also pale skin, while the child’s forehead and limbs remain cool at this time. Such symptoms are caused by spasms of peripheral vessels, resulting in a violation of heat transfer.

The treatment tactics for such fever and ordinary hyperthermia are somewhat different. The child should be given plenty of warm liquid to drink, and the skin should be massaged and rubbed. In order to treat white fever, it is necessary to supplement the combination of Diphenhydramine and Analgin with some antispasmodic drug.

Since three drugs are administered simultaneously, this mixture is called a triad. As a rule, the third drug is injectable “No-spa”, the main active ingredient of which is drotaverine. This medicine eliminates vascular spasms by provoking their expansion. You can use “No-shpu” if the baby is over 1 year old.

Often, No-shpu is replaced with another medicine that has a similar effect - Papaverine. It is available in the form of a solution with a concentration of 2%, and its use is permitted in children from six months of age. This medication effectively eliminates vascular spasms and dilates blood vessels. If the child's condition is severe, the doctor may recommend the additional use of Dexamethasone or other drugs.

We reviewed the instructions for use for injections of “Analgin” with “Diphenhydramine”.

Compound

A potent lytic drug in injections is usually used by emergency doctors when they need to quickly “bring down” a fever that is too high. The classic composition of this complex drug consists of three main components. Each of them alleviates the patient's condition.

Composition of the lytic mixture:

1. Analgin.

His share is 50% of the rest. It is an antipyretic analgesic.

1. Diphenhydramine.

Enhances the activity of Analgin. His share is 1% of the rest. This is an antihistamine that relieves allergic reactions. Additionally, it has a sedative effect. Can be replaced with Suprastin or Tavegil.

1. Papaverine.

Antispasmodic, dilates blood vessels. Belongs to the group of opium alkaloids. Increases heat transfer, reduces the risk of seizures. Its part is only 0.1% of the total composition. Can be replaced with No-shpa.

Important! When combined together in one mixture, these drugs do not form any new composition. They just enhance each other's effect. All the ingredients of a lytic remedy do not cure any disease. They only jointly relieve the acute symptoms of the inflammatory process, that is, they quickly “bring down” the fever.

Reviews

Reviews about the use of the combination of Diphenhydramine and Analgin are usually positive. This is due to the fact that the effect of the drug develops extremely quickly, allowing the child to eliminate fever in the shortest possible time. Side effects due to the use of medications do not develop as often. However, it should be taken into account that the drugs should be taken with extreme caution, like any other medications when treating children. If injectable forms of medications are used, they should be administered under medical supervision.

"Analgin" with "Diphenhydramine" in tablets for children

It is worth noting that the use of solutions is more dangerous than the use of tablet forms of drugs, since the likelihood of developing side symptoms is higher. However, the use of tablets is not always possible due to the baby’s age; he may not be able to swallow them.

If a child needs to drink “Analgin” with “Diphenhydramine”, then the pills are given to him in turn, and he must wash each one down with water. Dosages for tablet forms of drugs are similar.

Dosing by age

For pain and high fever, you can use analgin with diphenhydramine in combination in the form of pills or injections.

We do not recommend giving an injection to a small child without a doctor, as the baby may have an individual intolerance to the solution.

It is better to make the solution intramuscularly, since the gastrointestinal tract is not damaged and the components begin to act faster. There are norms for a ready-made composition: For an adult and a child from 10 years old, 1–2 ml/2 times every 24 hours; for a younger child, from 3 years old, 0.2 ml per 10 kg of weight. But in total no more than 1 ml.

Before the injection, carefully recalculate the patient’s weight and mg of solution, otherwise irreparable harm can be caused to the patient. It is better for the child to try to relieve the fever with suppositories or other drugs before injecting the solution.